What Is Vitamin K2 Powder?
Vitamin K2, scientifically known as menaquinone, is a fat-soluble vitamin that plays a critical role in calcium metabolism, cardiovascular health, and bone mineralization. Among its various subtypes, MK-4 (short-chain menaquinone) and MK-7 (long-chain menaquinone) are the most biologically significant and commercially relevant forms used in dietary supplement formulation and functional food manufacturing.
The naming convention follows a straightforward system: "M" refers to menaquinone, "K" denotes vitamin K, and the numerical suffix indicates the number of isoprenoid side chain repeating units. MK-7, in particular, has gained considerable attention in the nutraceutical industry due to its extended half-life in the bloodstream and superior bioavailability compared to MK-4, making it the preferred form for supplementation at lower dosage levels.
Extract Makers supplies pharmaceutical-grade Vitamin K2 Powder in both MK-4 and MK-7 forms, specifically formulated for use in dietary supplements, functional foods, and nutritional fortification applications. Our bulk Vitamin K2 Powder is manufactured under stringent quality control protocols, offering consistent potency, excellent batch-to-batch reproducibility, and full compliance with international food safety standards.
Physicochemical Properties of Vitamin K2 Powder
Understanding the physicochemical profile of Vitamin K2 Powder is essential for formulators, product developers, and procurement specialists evaluating its suitability across different applications.
- Solubility: Vitamin K2 is insoluble in water but readily soluble in organic solvents and vegetable oils. This lipophilic nature is important to consider during formulation, particularly when developing oil-based softgel capsules, emulsified beverages, or fat-based delivery systems.
- Appearance: Fine, free-flowing yellowish to off-white powder, depending on the form and excipient matrix used.
- Stability: Long-chain MK-7 demonstrates greater metabolic stability than short-chain MK-4, contributing to sustained plasma levels after oral ingestion.
- Excipient Matrix: Our MK-7 product uses a carbohydrate-based pharmaceutical excipient to enhance powder flowability, improve dispersibility in dry blending, and support stability during storage.
Vitamin K2 Powder Specifications
Certificate of Analysis — Vitamin K2 MK-7 (1.3%)
| Item | Specification | Result |
|---|---|---|
| Purity (HPLC, Menaquinone-7) | ≥1.3% (>13,000 μg/g) | 1.37% |
| Pharmaceutical Excipient (Carbohydrate) | ≥90.0% | 90.60% |
| pH | 5.5–8.0 | 6.6 |
| Loss on Drying | ≤10.0% | 7.50% |
| Residue on Ignition | ≤0.1% | <0.1% |
| Reducing Sugar | ≤0.2% | <0.2% |
| Starch | Negative | Negative |
| Fatty Acid | Negative | Negative |
| Heavy Metals | ≤10 ppm | <10 ppm |
| Arsenic | ≤2 ppm | Complies |
| Pesticide Residues | Negative | Negative |
| Total Aerobic Count (CFU/g) | ≤1,000 | Complies |
| Yeasts & Molds (CFU/g) | ≤100 | Complies |
| Salmonella spp. | Negative | Negative |
| E. coli | Negative | Negative |
All analytical testing is conducted using validated HPLC methodologies, and each production batch is accompanied by a full Certificate of Analysis to support your quality assurance documentation and regulatory submissions.
Health Benefits and Functional Advantages of Vitamin K2
Vitamin K2 Powder has been the subject of growing scientific interest in recent decades, with research examining its diverse physiological roles. The following functional benefits are recognized within the nutraceutical and clinical nutrition communities:
1. Cardiovascular Health Support
Vitamin K2 activates matrix Gla protein (MGP), a key inhibitor of arterial calcification. By directing calcium away from arterial walls and toward bone tissue, Vitamin K2 may help support long-term cardiovascular health and arterial flexibility.
2. Bone Density and Skeletal Integrity
Vitamin K2 is required for the carboxylation of osteocalcin, the bone protein responsible for binding calcium into the bone matrix. Regular intake of K2 in adequate amounts has been associated with improved bone mineral density and reduced fracture risk, making it a valuable ingredient in bone health supplement formulations.
3. Dental Health Promotion
Emerging research suggests that Vitamin K2 may activate specific proteins involved in dental calcification and enamel strength, supporting oral health from a nutritional standpoint. This makes it a relevant ingredient for next-generation oral health supplements.
4. Potential Role in Cancer Risk Reduction
Preliminary research has explored Vitamin K2's potential in modulating cell growth pathways. While further clinical evidence is needed, early findings have generated interest in its use within integrative oncology nutrition protocols.
Note: The above benefits are based on available scientific literature and are provided for informational and B2B formulation reference purposes. These statements have not been evaluated by regulatory bodies as drug claims.
Industry Applications of Vitamin K2 Powder
Vitamin K2 Powder is a versatile ingredient with established and emerging applications across multiple industries:
Dietary Supplements & Nutraceuticals
The primary application domain for Vitamin K2 Powder is dietary supplementation. It is widely formulated into:
- Hard-shell capsules and soft-gel capsules
- Tablet formulations (often combined with Vitamin D3)
- Effervescent tablets and drink powders
- Multivitamin complexes and bone health stacks
- Sports nutrition and recovery formulas
Functional Food & Beverage Fortification
As consumer demand for fortified foods continues to grow, Vitamin K2 is increasingly used as a nutritional fortification agent in:
- Fortified dairy products and plant-based milk alternatives
- Nutritional bars and meal replacement powders
- Functional beverages designed for bone and heart health positioning
Pharmaceutical Preparations
Vitamin K2 is recognized in several pharmacopoeias and is incorporated into pharmaceutical-grade preparations targeting osteoporosis management, coagulation support, and metabolic bone disease protocols.
Cosmetic and Dermatological Products
Emerging applications include topical formulations where Vitamin K2 is explored for its role in skin calcification and dermal health — a niche but growing segment of the personal care ingredients market.
Quality Standards and Certifications
Extract Makers operates a GMP-certified manufacturing facility with comprehensive quality management systems in place to support the production of high-purity Vitamin K2 Powder. Our facility and products comply with the following international standards and certifications:
- GMP (Good Manufacturing Practice) — Ensuring consistent production quality
- HACCP — Hazard Analysis and Critical Control Points certified
- ISO 22000 — Food safety management system
- ISO 9001 — Quality management system
- Kosher Certified — Suitable for Kosher-compliant formulations
- Halal Certified — Suitable for Halal-compliant formulations
- FDA Registration — Manufactured in an FDA-registered facility
These certifications reflect our commitment to producing ingredients that meet the expectations of international supplement brands, contract manufacturers, and regulatory-conscious importers.
Why Source Vitamin K2 Powder from Extract Makers?
For procurement managers, formulation chemists, and brand owners evaluating bulk Vitamin K2 suppliers, Extract Makers offers a combination of technical capability, regulatory compliance, and supply chain reliability that is difficult to match:
- Verified Potency: Each batch is HPLC-tested and released only upon meeting defined purity thresholds.
- Batch-to-Batch Consistency: Standardized extraction and blending processes ensure uniform particle size distribution, potency, and color across all production runs.
- Full Documentation Support: COA, MSDS, spec sheets, and regulatory documentation are available for every shipment.
- Custom Potency and Blending: We support custom-strength formulations and co-blending with complementary ingredients such as Vitamin D3, calcium, and magnesium.
- Scalable Supply: Whether you require small R&D quantities or multi-ton commercial orders, we maintain the capacity and inventory to fulfill your requirements reliably.
Packaging Options
Extract Makers provides flexible packaging configurations to accommodate projects at every scale:
- 1 kg – 5 kg: Double-sealed aluminum foil bags, ideal for sampling, R&D, and small-batch production
- 10 kg – 20 kg: Corrugated export cartons with inner liner protection
- 10 kg – 30 kg: Fiber drums with moisture-barrier lining for bulk commercial orders
Private Label and Custom Packaging
We offer fully customized private label packaging services. Our team can produce finished bags or containers printed with your brand logo, product name, and regulatory labeling — helping you reduce lead times and streamline your go-to-market process.
Free Samples Available
Extract Makers provides complimentary samples (typically 10–20 g) to qualified buyers for quality evaluation and formulation testing purposes. Samples are dispatched with a full Certificate of Analysis. For high-value product grades, sample availability is subject to confirmation. Please contact us to initiate a sample request.
Shipping and Logistics
We offer a comprehensive range of international shipping options to serve customers across North America, Europe, Southeast Asia, and beyond:
- Express Courier (Orders under 1 ton): DHL, FedEx, UPS, EMS, and other major international courier services
- Rail Freight: Available for customers in regions with accessible rail connectivity, offering a cost-effective alternative to air freight for mid-volume orders
- Sea Freight: Recommended for large-volume orders, with full export documentation and customs clearance support
All shipments are accompanied by complete export documentation, including commercial invoice, packing list, COA, and applicable phytosanitary or health certificates as required by the destination country.
Storage Recommendations
To preserve the potency, color stability, and microbiological integrity of Vitamin K2 Powder:
- Store in a cool, dry location away from direct sunlight and heat sources
- Recommended storage temperature: below 25°C
- Keep packaging tightly sealed to prevent moisture absorption
- Avoid prolonged exposure to UV light, which can degrade menaquinone activity
Shelf Life: 24 months from the date of manufacture when stored under recommended conditions.
After-Sale Service and Quality Guarantee
Extract Makers stands behind the quality of every shipment. All products are covered by a two-year shelf life guarantee from the production date. In the unlikely event that a product fails to meet the agreed specifications upon receipt, we operate a straightforward return and refund policy based on the quantity returned and verified non-conformance documentation.
Our dedicated customer service team is available to assist with technical inquiries, regulatory documentation requests, formulation guidance, and post-shipment support.
Request a Quote or Sample
To request pricing, bulk quotes, technical documentation, or free samples of our Vitamin K2 Powder (MK-4 or MK-7), please contact our team directly:
Email: [email protected]
Extract Makers maintains a portfolio of over 2,000 botanical extracts, nutritional ingredients, and functional raw materials. If you are looking for a specific ingredient not listed on our website, we encourage you to reach out — our sourcing and production team can assist with both standard and custom ingredient requirements.












