What Is Scutellaria Baicalensis Root Extract?
Scutellaria Baicalensis Root Extract is a standardized botanical ingredient derived from the dried roots of Scutellaria baicalensis Georgi, a perennial herb widely recognized in traditional Chinese medicine under the name Huang Qin. The plant is also commonly referred to as Chinese Skullcap or Baikal Skullcap, and it has been utilized for centuries across Eastern Asia for its broad-spectrum biological activity.
The primary bioactive compound isolated from this root extract is baicalin (baicalein-7-glucuronide), a flavonoid glycoside that has attracted significant scientific and commercial interest in the nutraceutical, cosmetic, and pharmaceutical sectors. Extract Makers supplies this ingredient in a highly concentrated, standardized form — with baicalin content confirmed at 80% to 90% by HPLC analysis — making it a premium-grade raw material suitable for formulation and manufacturing at scale.
Botanical Source and Raw Material Traceability
The raw material is sourced from cultivated Scutellaria baicalensis plants, with roots harvested at optimal maturity to ensure maximum flavonoid accumulation. The plant thrives in the temperate grasslands and mountain slopes of northern and northeastern China, where natural growing conditions contribute to consistent phytochemical profiles.
Extract Makers places strong emphasis on raw material traceability and supply chain transparency. From field cultivation and root harvest to extraction and finished ingredient production, each step of the process is documented and auditable — providing our clients with full confidence in ingredient origin, agricultural practices, and batch-to-batch consistency.
Extraction and Manufacturing Process
The extract is produced using a controlled aqueous-alcohol extraction process, followed by purification, concentration, and spray drying. This method is specifically optimized to preserve the structural integrity of baicalin while minimizing degradation of co-occurring flavonoids such as baicalein and wogonin.
Key process controls include:
- Standardized extraction ratios to ensure consistent active ingredient yield
- Chromatographic purification for removal of non-target compounds
- Spray drying under controlled temperature parameters to maintain powder quality
- In-process quality checks at each critical manufacturing stage
All production is carried out in a GMP-certified manufacturing facility, with full compliance to international quality management standards.
Active Ingredient: Baicalin
Baicalin is the principal flavonoid glycoside found in Scutellaria baicalensis root and is responsible for the majority of the extract's documented bioactive properties. It belongs to the flavone subclass and has been extensively studied for its antioxidant, anti-inflammatory, antimicrobial, and hepatoprotective characteristics.
Key Bioactive Properties of Baicalin
- Antioxidant activity: Baicalin effectively scavenges reactive oxygen species (ROS) and free radicals, helping to mitigate oxidative stress at the cellular level.
- Anti-inflammatory mechanisms: It modulates key inflammatory signaling pathways, including the inhibition of NF-κB and the suppression of pro-inflammatory cytokine production.
- Bacteriostatic effects: Baicalin demonstrates inhibitory activity against a range of gram-positive and gram-negative bacteria, supporting its use in antimicrobial formulations.
- Hepatoprotective support: Research indicates that baicalin may assist in liver cell protection, supporting detoxification pathways and reducing hepatic oxidative damage.
- Cholesterol management: Preliminary evidence suggests a role in supporting healthy lipid metabolism and reducing LDL oxidation.
These properties make Scutellaria Baicalensis Root Extract a multifunctional ingredient well suited to diverse formulation applications across health, beauty, and clinical nutrition sectors.
Physical and Chemical Characteristics
| Property | Description |
|---|---|
| Appearance | Light yellow fine powder |
| Taste | Bitter |
| Odor | Characteristic |
| Solubility | Soluble in hot acetic acid; slightly soluble in chloroform and nitrobenzene; poorly soluble in water, methanol, ethanol, and acetone |
| Particle Size | 100% through 80 mesh |
| Active Ingredient | Baicalin ≥85% (HPLC) |
Solubility and Formulation Notes
Baicalin exhibits limited water solubility under ambient conditions, which is an important consideration for aqueous-based formulations. For applications requiring enhanced solubility, formulators may consider the use of cyclodextrin complexation, nano-emulsification, or co-solvent systems. Its stability is generally favorable under dry storage conditions, though exposure to prolonged heat, moisture, and UV light should be avoided to prevent degradation of active content.
Certificate of Analysis (CoA) — Representative Batch
| Test Item | Specification | Test Method | Result |
|---|---|---|---|
| Appearance | Light Yellow Powder | Organoleptic | Conforms |
| Odor | Characteristic | Organoleptic | Conforms |
| Mesh Size | 100% through 80 mesh | Organoleptic | Conforms |
| Loss on Drying | ≤5.0% | USP37 \<921> | 3.80% |
| Ignition Ash | ≤5.0% | USP37 \<561> | 3.30% |
| Baicalin (Active) | ≥85% | HPLC | 90.30% |
| Lead (Pb) | ≤3.0 mg/kg | USP37 \<233> | Conforms |
| Arsenic (As) | ≤2.0 mg/kg | USP37 \<233> | Conforms |
| Cadmium (Cd) | ≤1.0 mg/kg | USP37 \<233> | Conforms |
| Mercury (Hg) | ≤1.0 mg/kg | USP37 \<233> | Conforms |
| Total Plate Count | ≤1000 cfu/g | USP37 \<61> | 500 cfu/g |
| Yeast & Mold | ≤100 cfu/g | USP37 \<61> | 35 cfu/g |
| E. Coli | Negative | USP30 \<62> | Conforms |
| Salmonella | Negative | USP30 \<62> | Conforms |
| Shelf Life | 24 months | — | — |
All test results are based on representative production batches. Full CoA documentation is available upon request.
Industry Applications
Scutellaria Baicalensis Root Extract is a commercially versatile ingredient with a broad range of established applications across multiple industries:
Dietary Supplements and Nutraceuticals
Baicalin powder is widely incorporated into capsule, tablet, softgel, and powder formulations targeting antioxidant support, liver health, immune function, and general wellness. It is frequently found in combination formulations with other adaptogenic herbs and polyphenol-rich botanicals.
Cosmetics and Skincare
The anti-inflammatory and antioxidant profile of baicalin makes it a sought-after active in skincare formulations. It is used in serums, creams, toners, and masks designed to address skin sensitivity, redness, oxidative aging, and environmental stress. Its compatibility with a range of cosmetic carrier systems supports broad formulation utility.
Functional Foods and Beverages
Scutellaria Baicalensis Root Extract is finding increasing use in functional food and beverage products, particularly in Asian markets, where consumer awareness of traditional botanical ingredients is high. It can be incorporated into health tonics, herbal teas, and fortified food products.
Pharmaceutical and Cosmeceutical Research
Baicalin continues to be an active subject of pharmaceutical research, particularly in the fields of inflammation, neuroprotection, and metabolic health. Manufacturers and research institutions sourcing this ingredient for clinical or formulation development will find our standardized extract ideal for consistent experimental and commercial application.
Quality Standards and Certifications
Extract Makers operates under a rigorous quality assurance framework designed to meet the highest international standards for botanical ingredient manufacturing.
Our facility and products carry the following certifications:
- GMP (Good Manufacturing Practice) — certified manufacturing environment
- ISO 9001 — quality management systems
- ISO 22000 — food safety management
- HACCP — hazard analysis and critical control points
- Kosher Certified
- Halal Certified
- FDA Facility Registration
Every production batch of Scutellaria Baicalensis Root Extract undergoes full analytical testing, including HPLC-based quantification of baicalin, heavy metal screening, microbiological assessment, and physical characterization. Third-party laboratory verification is available upon request for clients requiring additional documentation for import compliance or product registration purposes.
Packaging Specifications
Extract Makers offers flexible packaging configurations to accommodate the purchasing requirements of ingredient buyers, formulators, and distributors at all scales:
- 1 kg – 5 kg: Double-sealed aluminum foil bags
- 10 kg – 20 kg: Corrugated cartons with inner polyethylene liner
- 10 kg – 30 kg: Fiber drums with double inner plastic bags (N.W. 25 kg; Drum dimensions: I.D. 35 cm × H 51 cm)
Private Label and Custom Packaging
For brands and distributors seeking a white-label or private-label solution, Extract Makers offers fully customized packaging services. We can print your brand logo, product name, and design directly onto the packaging — enabling you to bring finished or semi-finished products to retail channels without the additional overhead of in-house packaging operations. This service is particularly valuable for emerging supplement brands, regional distributors, and contract manufacturers.
Storage Recommendations
To maintain the quality, potency, and stability of Scutellaria Baicalensis Root Extract throughout its shelf life, the following storage conditions are recommended:
- Store in a cool, dry environment with controlled temperature
- Protect from moisture, direct light, and oxygen exposure
- Keep containers tightly sealed when not in use
- No antioxidant additives are used in this product; proper storage conditions are essential for preserving active ingredient integrity
Shelf life: 24 months from date of manufacture under recommended storage conditions.
Shipping and Logistics
Extract Makers supports global distribution with flexible shipping arrangements tailored to order volume and destination:
- Small to mid-sized orders (below 1 metric ton): Available via DHL, FedEx, UPS, EMS, and other international express courier services
- Large-volume orders: Sea freight and railway shipping options are available depending on destination and logistical requirements
All shipments are accompanied by full documentation, including Certificate of Analysis, Material Safety Data Sheet (MSDS), and relevant customs and compliance documents to facilitate smooth import clearance in your country.
Free Samples Available
Extract Makers understands that quality verification is a critical step in the ingredient sourcing process. We offer complimentary samples of 10g–20g to qualified buyers for laboratory evaluation and formulation testing. Sample requests for higher-value or specialized grades are subject to confirmation.
To request a sample or obtain a product quotation, please contact our team directly at [email protected].
After-Sales Support and Quality Guarantee
We are committed to long-term partnerships with our clients and stand behind the quality of every product we supply. Our after-sales commitments include:
- 24-month product guarantee under specified storage conditions
- Hassle-free return policy: In the event that a delivered product does not meet agreed specifications, we will process a refund proportional to the quantity returned
- Responsive technical support for formulation, regulatory, and logistics inquiries
Why Source Scutellaria Baicalensis Root Extract from Extract Makers?
- ✔ High-purity standardized extract with baicalin content verified at 90.30% by HPLC
- ✔ GMP-certified, multi-standard compliant manufacturing facility
- ✔ Full traceability from botanical source to finished ingredient
- ✔ Flexible MOQ and packaging options for brands of all sizes
- ✔ Comprehensive documentation package for regulatory and import compliance
- ✔ Private label and custom packaging services available
- ✔ Reliable global shipping with responsive account management
Contact Us
Extract Makers maintains a portfolio of over 2,000 plant extracts, botanical ingredients, and nutritional raw materials — not all of which are listed on our website. If you are looking for a specific ingredient or grade that is not immediately visible, please reach out to our team directly. We will be happy to assist with sourcing, technical specifications, pricing, and logistics.
📧 Email: [email protected]
We welcome inquiries from supplement manufacturers, cosmetic formulators, pharmaceutical companies, contract manufacturers, trading companies, importers, and brand owners worldwide.
