What Is Urolithin A?
Urolithin A is a naturally occurring bioactive compound belonging to the urolithin family of isomers. In the human body, it is produced endogenously as a gut-derived metabolite, formed when intestinal bacteria convert ellagitannins and ellagic acid — polyphenolic compounds found in foods such as pomegranates, walnuts, and certain berries — into this biologically active molecule.
From a chemical standpoint, Urolithin A is characterized by the molecular formula C₁₃H₈O₄, with a CAS number of 1143-70-0. In its purified bulk form, it presents as a yellowish beige fine powder, offering excellent handling characteristics suitable for downstream formulation use across multiple industries.
Biological Activity and Functional Benefits
Mitochondrial Health and Anti-Aging Potential
One of the most extensively researched properties of Urolithin A powder is its role in supporting mitochondrial function. Scientific studies suggest that Urolithin A may activate a cellular process known as mitophagy — the selective clearance of damaged or dysfunctional mitochondria that accumulate as a result of natural aging. By facilitating the removal of these impaired organelles and promoting the biogenesis of healthy mitochondria, Urolithin A may contribute to improved cellular energy metabolism and overall cellular resilience.
This mechanism positions Urolithin A as a highly relevant compound in the growing anti-aging and longevity supplement market, where mitochondrial health is increasingly recognized as a cornerstone of healthy aging at the cellular level.
Skin Health and Neuroprotective Properties
Beyond mitochondrial support, emerging research indicates that Urolithin A may offer additional functional benefits relevant to cosmetic and nutraceutical applications:
- Skin Brightening: Preliminary studies suggest that Urolithin A may contribute to a more even skin tone by modulating melanin synthesis pathways, making it a candidate active ingredient in whitening and anti-aging skincare formulations.
- Neuroprotection: Certain research findings indicate that Urolithin A may exert neuroprotective effects, potentially supporting neuronal health through antioxidant and anti-inflammatory mechanisms. This opens potential application avenues in cognitive health and brain wellness supplements.
Product Specifications and Certificate of Analysis
Extract Makers maintains rigorous quality control standards across every batch of Urolithin A powder. The following Certificate of Analysis reflects our standard product specification:
| Parameter | Specification | Typical Result | Test Method |
|---|---|---|---|
| Purity | ≥99.0% | 100.1% | HPLC |
| Appearance | Yellowish Beige Powder | Conforms | Visual |
| Identification | Spectrum corresponds to reference | Conforms | ¹H NMR |
| Water Content | ≤1.0% | 0.12% | Karl Fischer |
| Heavy Metals (Total) | ≤1.00 mg/kg | <1.00 mg/kg | ICP-MS |
| Lead (Pb) | ≤1.00 mg/kg | <1.00 mg/kg | ICP-MS |
| Arsenic (As) | ≤1.00 mg/kg | <1.00 mg/kg | ICP-MS |
| Cadmium (Cd) | ≤1.00 mg/kg | <1.00 mg/kg | ICP-MS |
| Mercury (Hg) | ≤0.10 mg/kg | <0.10 mg/kg | ICP-MS |
| Total Plate Count | ≤1000 cfu/g | 20 cfu/g | USP-NF 2022 |
| Total Yeast & Mold | ≤100 cfu/g | 10 cfu/g | USP-NF 2022 |
| Salmonella | Negative | Negative | USP-NF 2022 |
| E. Coli | Negative | Negative | USP-NF 2022 |
| Shelf Life | 24 months | — | — |
Conclusion: Sample Qualified.
All analytical data is supported by independent third-party laboratory testing reports, available upon request.
Quality Standards and Certifications
Extract Makers operates under a fully compliant, standards-driven manufacturing environment. Our production facility and product portfolio are backed by the following certifications:
- GMP (Good Manufacturing Practice) — Manufactured in a GMP-certified facility
- FDA Registration
- ISO 9001 — Quality Management System
- ISO 22000 — Food Safety Management
- HACCP — Hazard Analysis and Critical Control Points
- Kosher Certified
- Halal Certified
These certifications reflect our commitment to product safety, batch-to-batch consistency, and compliance with international regulatory requirements — critical factors for manufacturers, brand owners, and importers operating in regulated markets.
Industry Applications
Urolithin A powder is a versatile active ingredient with growing demand across several high-value sectors:
Dietary Supplements
Urolithin A is increasingly incorporated into premium supplement formulations targeting longevity, healthy aging, muscle recovery, and mitochondrial support. It is compatible with capsule, tablet, softgel, and powder stick-pack formats.
Cosmetics and Skincare
Due to its potential skin-brightening and antioxidant properties, Urolithin A is gaining traction as a functional ingredient in serums, creams, and anti-aging topical formulations.
Functional Foods and Beverages
As consumer interest in bioactive nutraceuticals grows, Urolithin A represents an emerging ingredient for functional food and beverage product developers seeking science-backed differentiation.
Sports Nutrition
Research interest in Urolithin A's role in supporting mitochondrial biogenesis and muscle cell health makes it a candidate ingredient in performance and recovery-focused sports nutrition products.
Physical and Chemical Properties
| Property | Detail |
|---|---|
| Chemical Name | Urolithin A |
| CAS Number | 1143-70-0 |
| Molecular Formula | C₁₃H₈O₄ |
| Appearance | Yellowish Beige Fine Powder |
| Purity | ≥99.0% (HPLC) |
| Water Content | ≤1.0% |
| Solubility | Soluble in DMSO and organic solvents; limited aqueous solubility |
| Stability | Stable under recommended storage conditions |
Storage and Handling
To preserve the integrity, potency, and shelf life of Urolithin A powder, the following storage conditions are recommended:
- Store in a tightly sealed container away from moisture and humidity
- Keep away from direct sunlight and sources of heat
- Maintain storage in a cool, dry environment
- Shelf life: 24 months from the date of manufacture when stored as directed in original, unopened packaging
Proper storage practices ensure product stability throughout the supply chain, from warehouse to finished product manufacturing.
Packaging Options
Extract Makers offers flexible packaging configurations to meet the diverse needs of bulk buyers, formulators, and private label brands:
- 1 kg – 5 kg: Double-sealed aluminum foil bags
- 10 kg – 20 kg: Corrugated export cartons with inner lining
- 10 kg – 30 kg: Fiber drums suitable for larger bulk orders
Private Label and Custom Packaging
For brand owners and distributors looking to bring retail-ready products to market, we offer comprehensive private label packaging services. Our team can customize packaging artwork, apply your brand logo and design, and prepare finished bags for direct retail or e-commerce distribution. This eliminates the need for separate packaging operations and significantly reduces lead time to market.
Free Sample Policy
We understand that quality verification is a critical part of the sourcing process. Extract Makers offers complimentary samples of Urolithin A powder — typically ranging from 10 g to 20 g — to qualified buyers for quality evaluation and formulation testing. Please note that due to the premium nature of this compound, sample availability and quantity may be subject to confirmation.
To request a free sample, contact our team directly at [email protected].
Shipping and Logistics
Extract Makers supports global distribution with flexible shipping solutions tailored to order volume:
- Small to medium orders (under 1 metric ton): Available via DHL, FedEx, UPS, EMS, and other international express courier services
- Large volume orders: Sea freight and railway transport options are available depending on destination and logistics requirements
Our logistics team works with buyers to select the most cost-efficient and time-appropriate shipping method, providing full documentation support including COA, MSDS, and customs compliance paperwork.
After-Sales Support and Quality Guarantee
Customer satisfaction and supply chain reliability are fundamental to how Extract Makers operates. Our post-purchase commitments include:
- 24-month product quality guarantee — All products are covered within their stated shelf life
- Hassle-free return policy — If any product does not meet agreed specifications, we provide a proportional refund based on the returned quantity
- Dedicated account support — Our team is available to assist with technical questions, regulatory documentation, and reorder coordination
Why Source Urolithin A Powder from Extract Makers?
Manufacturers, formulators, importers, and distributors across North America, Europe, and Asia-Pacific choose Extract Makers as their preferred Urolithin A supplier for the following reasons:
- ≥99.0% purity confirmed by HPLC — pharmaceutical-grade quality suitable for demanding formulations
- Full certification stack — GMP, FDA, ISO 9001, ISO 22000, HACCP, Kosher, and Halal
- Independent third-party testing — Transparent quality documentation available for every batch
- Flexible MOQ and packaging — Scalable from sample quantities to multi-kilogram bulk orders
- Competitive wholesale pricing — Factory-direct supply eliminates unnecessary intermediary costs
- Private label capability — End-to-end branded packaging support for OEM and retail customers
- Reliable logistics — Established global shipping infrastructure with full documentation support
Contact Us for Wholesale Pricing and Samples
Whether you are a supplement brand, contract manufacturer, cosmetic formulator, or wholesale distributor, Extract Makers is ready to support your Urolithin A sourcing requirements with consistent quality, competitive pricing, and professional service.
To request a free sample, obtain a wholesale price quote, or discuss bulk order logistics, please reach out to our team:
📧 Email: [email protected]
We also supply over 2,000 specialty ingredients across the plant extract, nutraceutical, cosmetic active, and fine chemical categories. If you are looking for a specific ingredient not listed on our site, please contact us — our team can source and supply a wide range of raw materials to meet your formulation needs.
