What Is Gardenia Extract Genipin Powder?
Gardenia Extract Genipin Powder is a high-purity bioactive compound derived from the fruit of Gardenia jasminoides Ellis, a perennial evergreen flowering plant belonging to the Rubiaceae (coffee) family. Widely cultivated across East Asia — particularly in China, Japan, and Korea — gardenia fruit has a long-established history in traditional herbal medicine and is now recognized globally as a valuable source of iridoid glycoside compounds.
The primary active constituent present in gardenia fruit extract is geniposide, a naturally occurring iridoid glycoside. Through a controlled enzymatic or acid hydrolysis reaction followed by concentration and purification processes, geniposide is converted into its aglycone form — genipin — yielding a white crystalline powder with exceptional biochemical reactivity and broad industrial applicability.
Extract Makers supplies pharmaceutical-grade Gardenia Extract Genipin Powder with a standardized assay of ≥98% genipin, making it one of the highest-purity natural genipin products available on the bulk ingredients market.
Key Features of High-Purity Genipin (98%)
- Natural origin: Sustainably sourced from Gardenia jasminoides fruit
- High purity: Genipin assay ≥98% (verified at 99.26% in current batch)
- Versatile functionality: Effective as a natural cross-linking agent, functional food ingredient, and biomedical material
- Broad industry applications: Suitable for pharmaceutical, nutraceutical, cosmetic, and biomedical sectors
- Fully compliant: Manufactured under GMP conditions with HACCP, ISO22000, ISO9001, Kosher, Halal, and FDA compliance
Botanical Source and Extraction Process
Raw Material Origin
The botanical source for Gardenia Extract Genipin Powder is the dried ripe fruit of Gardenia jasminoides Ellis (Zhī Zǐ), a plant that thrives in subtropical and temperate climates. High-quality raw material is selectively harvested from cultivated and traceable plantation sources, ensuring consistent geniposide content in the starting material — a critical factor for achieving high final-product purity.
Production Process
The manufacturing of genipin from gardenia fruit involves a multi-step process:
- Raw material preparation: Dried gardenia fruits are cleaned, inspected, and prepared for extraction.
- Water or solvent extraction: Geniposide is extracted from the fruit using controlled aqueous or solvent-based extraction methods.
- Enzymatic or acid hydrolysis: Extracted geniposide undergoes hydrolysis to cleave the glucose moiety, converting geniposide into its aglycone — genipin.
- Purification and concentration: The hydrolysate is filtered, concentrated, and purified through chromatographic or recrystallization techniques to achieve ≥98% purity.
- Drying and milling: The purified compound is spray- or vacuum-dried, then milled to achieve a fine white powder with 100% pass through an 80-mesh screen.
- Quality testing and release: Each batch undergoes rigorous in-house and third-party testing prior to release.
This precise, reproducible manufacturing workflow ensures batch-to-batch consistency — a quality benchmark that is especially critical for pharmaceutical and biomedical formulators.
Certificate of Analysis (CoA)
The following represents standard test results for our Gardenia Extract Genipin Powder (Genipin 98%):
| Test Item | Standard | Result |
|---|---|---|
| Appearance | White Powder | Complies |
| Assay (Genipin) | ≥98% | 99.26% |
| Loss on Drying | ≤5.0% | Complies |
| Sulphated Ash | ≤2.0% | Complies |
| Heavy Metals | ≤20 PPM | Complies |
| Mesh Size | 100% pass 80 mesh | 100% pass 80 mesh |
| Total Plate Count | ≤1,000 cfu/g | <1,000 cfu/g |
| Yeast & Mould | ≤100 cfu/g | <100 cfu/g |
| E. Coli | Negative | Negative |
| Salmonella | Negative | Negative |
Full batch-specific CoA documentation is available upon request. Third-party test reports from accredited laboratories can also be provided for due diligence and regulatory submission purposes.
Physical and Chemical Properties
| Property | Description |
|---|---|
| Chemical Name | Genipin |
| CAS Number | 6902-77-8 |
| Molecular Formula | C₁₁H₁₄O₅ |
| Molecular Weight | 226.23 g/mol |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in water, methanol, and ethanol; slightly soluble in acetone |
| Stability | Stable under recommended storage conditions; light and moisture sensitive |
| Purity | ≥98% by HPLC |
| Mesh Size | 100% through 80 mesh |
Functional Properties and Industry Applications
1. Natural Cross-Linking Agent for Biomaterials
One of the most scientifically significant properties of genipin is its ability to function as a natural, low-cytotoxicity cross-linking agent for proteins, collagen, gelatin, and chitosan. Compared to synthetic cross-linkers such as glutaraldehyde — which are associated with significant cytotoxicity — genipin offers a substantially safer biocompatibility profile while maintaining effective cross-linking efficiency.
This makes Gardenia Extract Genipin Powder a highly sought-after ingredient in:
- Biomedical scaffolds and artificial bone matrices
- Wound dressing materials and tissue engineering substrates
- Drug delivery systems and hydrogels
- Collagen and gelatin-based biomaterial formulations
2. Pharmaceutical and Nutraceutical Applications
Genipin exhibits a range of pharmacologically relevant bioactivities that have been extensively studied in the scientific literature:
- Anti-inflammatory activity: Genipin has been shown to modulate inflammatory pathways, making it relevant for formulations targeting inflammatory conditions.
- Hepatoprotective effects: Research has indicated potential benefits for liver health, with genipin studied for its role in supporting liver function and addressing liver-related pathologies.
- Cholesterol and gallbladder support: Genipin has been explored in the context of gallbladder disease management and bile acid metabolism.
- Digestive health: Its traditional application in gastrointestinal wellness aligns with modern research into digestive health support.
- Cardiovascular support: Emerging studies suggest that genipin may contribute to blood pressure modulation, positioning it as a candidate ingredient in cardiovascular wellness formulations.
These bioactivities make genipin of significant interest to formulators developing dietary supplements, herbal medicines, and functional food ingredients.
3. Cosmetics and Tattoo Ink Applications
Genipin possesses a unique and commercially valuable colorimetric property: when it comes into contact with free amino acids and proteins — such as those naturally present in skin cells — it undergoes a spontaneous reaction to produce a stable dark blue or navy blue pigment. This reaction is gradual, non-toxic, and long-lasting, which has led to the development of genipin-based semi-permanent tattoo creams and natural skin-marking formulations.
This application is gaining increasing attention from cosmetic brands and specialty ink manufacturers seeking naturally derived, biocompatible alternatives to synthetic pigments.
Quality Standards and Certifications
Extract Makers operates a fully integrated, GMP-compliant manufacturing facility with robust quality management systems in place. Our Gardenia Extract Genipin Powder is produced and tested to meet international regulatory and quality standards, including:
- GMP (Good Manufacturing Practice) — ensuring consistent production quality
- HACCP — hazard analysis and critical control points compliance
- ISO 22000 — food safety management system certification
- ISO 9001 — quality management system certification
- Kosher Certified — suitable for kosher dietary requirements
- Halal Certified — suitable for halal dietary requirements
- FDA Facility Registration — compliance with U.S. FDA regulations
These certifications reflect our commitment to supplying traceable, consistently high-quality botanical extracts to international buyers across pharmaceutical, nutraceutical, food, and cosmetic industries.
Solubility, Stability, and Storage Recommendations
Solubility: Genipin is soluble in water and common polar organic solvents including methanol and ethanol. This versatility supports its incorporation into a wide range of formulation matrices, including aqueous solutions, hydrogels, and solvent-based systems.
Stability: Genipin powder is chemically stable under normal conditions but is sensitive to light, heat, and moisture. Prolonged exposure to these conditions may reduce purity and potency.
Storage Recommendations:
- Store in a cool, dry, well-ventilated environment
- Recommended storage temperature: 2–8°C (refrigerated) for long-term storage; room temperature acceptable for short-term use
- Keep away from direct sunlight and moisture
- Reseal packaging immediately after use
Shelf Life: 24 months (2 years) from the date of manufacture under recommended storage conditions.
Packaging Specifications
Extract Makers offers flexible packaging options designed to accommodate both small-scale R&D procurement and large-volume commercial orders:
| Order Volume | Packaging Format |
|---|---|
| Sample quantities | 10g – 20g sealed pouches |
| Small to mid-scale orders | 1 kg – 5 kg aluminum foil bags |
| Standard commercial orders | 10 kg – 20 kg cartons with inner liner |
| Bulk industrial orders | 10 kg – 30 kg fiber drums |
Private Label and Custom Packaging
For brands and distributors looking to retail Gardenia Extract Genipin Powder under their own brand identity, Extract Makers provides comprehensive private label and custom packaging services. We can print your logo, brand design, and product specifications directly on the packaging — eliminating the need for in-house labeling operations and significantly reducing your time-to-market.
Shipping and Logistics
Extract Makers ships globally, with shipping methods tailored to order volume and destination:
- Small and sample orders (below 1 ton): DHL, FedEx, UPS, EMS, and other major international express carriers
- Large volume orders: Sea freight (FCL/LCL) and railway freight services available to most international destinations
All shipments are accompanied by full documentation, including CoA, MSDS, packing list, commercial invoice, and any additional customs or regulatory documents required by the destination country.
Free Sample Policy
We understand that quality verification is an essential part of the procurement decision-making process. Extract Makers offers complimentary product samples of Gardenia Extract Genipin Powder for qualified buyers:
- Standard sample size: 10g – 20g per request
- Samples are provided free of charge for evaluation purposes
- For high-value or specialized specifications, sample availability is subject to confirmation
Samples are shipped with full CoA and technical documentation to support your internal testing and formulation development.
After-Sales Support and Quality Guarantee
Extract Makers is committed to maintaining long-term partnerships with our clients through reliable after-sales support:
- 2-year product guarantee — all products are warranted for the duration of their stated shelf life
- Hassle-free return policy — if products fail to meet agreed specifications, returns and refunds are processed on a pro-rata basis according to the quantity returned
- Dedicated technical support — our team is available to assist with formulation questions, regulatory documentation, and application-specific guidance
Why Source Gardenia Extract Genipin Powder from Extract Makers?
Formulators, manufacturers, distributors, and importers choose Extract Makers as their preferred genipin supplier for the following reasons:
- Consistent high purity: Genipin assay verified at 99.26%, well above the ≥98% specification
- Traceable botanical sourcing: Raw material provenance documented from cultivation through to final product
- Full regulatory compliance: GMP, HACCP, ISO22000, ISO9001, Kosher, Halal, and FDA certifications
- Flexible order quantities: From R&D samples to full commercial volumes
- Custom packaging and private label capability
- Competitive bulk pricing with reliable lead times
- Comprehensive documentation support for international trade and regulatory submissions
- Responsive customer service and technical consultation
Request a Quote or Free Sample
To obtain a quotation, request a free sample, or discuss your specific requirements for Gardenia Extract Genipin Powder, please contact our team directly:
Email: [email protected]
Our specialists are available to assist with product specifications, custom formulation requirements, shipping logistics, and documentation needs. We welcome inquiries from manufacturers, brand owners, supplement formulators, research institutions, and international distributors.
Extract Makers maintains an extensive product portfolio of over 2,000 plant extracts, botanical ingredients, and nutritional raw materials. If you are looking for a specific ingredient not listed on our website, please reach out directly — our sourcing team can assist with custom procurement requests.
