Product Overview
Cnidium Monnieri Extract Osthole is a highly refined botanical active ingredient derived from the dried seeds of Cnidium monnieri (L.) Cusson, a flowering plant native to China and widely cultivated across East Asia. The premium-grade Osthole 98% presents as a fine white powder with exceptional purity, making it one of the most sought-after standardized plant extracts in the global nutraceutical, functional cosmetic, and dietary supplement ingredient markets.
Osthole (7-methoxy-8-(3-methyl-2-butenyl)-2H-chromen-2-one) is the primary bioactive coumarin compound isolated from Cnidium monnieri seeds. It has been extensively studied for its diverse biological activities and has a well-documented history of use in traditional herbal medicine systems. For ingredient buyers, formulation developers, and private label brand owners, this extract offers a compelling combination of high standardization, biological potency, and versatile application compatibility.
Botanical Source & Raw Material Background
- Plant Name: Cnidium monnieri (L.) Cusson
- Family: Apiaceae (Umbelliferae)
- Part Used: Dried mature seeds (Fructus Cnidii)
- Common Names: She Chuang Zi (Chinese), Common Cnidium, Monnier's Snowparsley
- Primary Growing Regions: Hebei, Jiangsu, Zhejiang, Sichuan provinces, China
The raw seeds are carefully harvested at optimal maturity, sorted, and cleaned to remove impurities before entering the extraction process. Consistent raw material sourcing from established cultivation bases ensures batch-to-batch stability in active compound content — a critical quality parameter for downstream formulators and finished product manufacturers.
Extraction & Manufacturing Process
Extract Makers employs a rigorous multi-step extraction and purification process designed to maximize Osthole yield while eliminating undesirable compounds:
- Raw material pre-treatment — Drying, grinding, and standardized particle size reduction
- Solvent extraction — Controlled extraction using food-grade or pharmaceutical-grade solvents to selectively isolate coumarin compounds
- Filtration & concentration — Multi-stage filtration followed by vacuum concentration
- Chromatographic purification — Column chromatography to achieve high-purity Osthole (up to 98%)
- Spray drying or vacuum drying — To produce consistent, free-flowing powder with low moisture content
- In-process quality testing — HPLC-based quantification at each production stage
This end-to-end process takes place within a GMP-certified manufacturing facility, ensuring pharmaceutical-grade manufacturing standards are applied throughout production.
Product Specifications
Extract Makers offers Cnidium Monnieri Extract across a full range of standardization levels to accommodate different formulation needs and budget requirements:
| Specification | Appearance | Intended Use |
|---|---|---|
| 10:1 Ratio Extract | Brown Powder | Traditional herbal blends, TCM-based formulations |
| 50:1 Ratio Extract | Brown Powder | High-concentration herbal preparations |
| Osthole 10% | Brown-Green Powder | Entry-level standardized extracts, herbal complexes |
| Osthole 20%–70% | Yellow-Green Powder | Mid-range nutraceutical and cosmetic applications |
| Osthole 80% | Light Yellow Powder | Advanced supplement formulations |
| Osthole 90% | White Powder | High-potency nutritional and functional products |
| Osthole 98% | White Powder | Pharmaceutical-grade, research, and premium formulations |
All specifications are verified by HPLC analysis, with certificates of analysis (COA) available for every batch upon request.
Key Chemical & Physical Properties
- Chemical Name: 7-Methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
- CAS Number: 484-12-8
- Molecular Formula: C₁₅H₁₆O₃
- Molecular Weight: 244.29 g/mol
- Appearance: White to off-white crystalline powder (at 98% purity)
- Solubility: Practically insoluble in water; soluble in ethanol, methanol, chloroform, DMSO, and other organic solvents
- Melting Point: Approximately 83–85°C
- Assay Method: HPLC
- Loss on Drying: ≤5%
- Heavy Metals: Compliant with USP/EP limits
- Mesh Size: 80 mesh (standard); finer mesh available upon request
Understanding solubility characteristics is especially important for formulation chemists: Osthole's lipophilic nature makes it well-suited for oil-based delivery systems, lipid capsules, soft gel formulations, and emulsion-based topical products.
Functional Properties & Reported Benefits
Research into Cnidium monnieri extract and its primary active constituent Osthole has highlighted several areas of biological activity relevant to product formulation:
Sexual Health & Hormonal Support
Osthole has been studied for its role in supporting male and female sexual health. It is believed to modulate nitric oxide signaling pathways and exhibit phosphodiesterase-inhibiting activity, making it a popular ingredient in men's health supplements and vitality formulas.
Bone Health & Density Support
Scientific literature suggests that Osthole may promote osteoblast activity and inhibit osteoclast-mediated bone resorption. This has generated significant interest from formulators developing bone health, osteoporosis-support, and post-menopausal wellness products.
Skin & Dermatological Applications
Cnidium monnieri has a long history of topical use in traditional medicine for managing pruritus, eczema, and fungal skin conditions. Osthole's reported antimicrobial and anti-inflammatory properties make it relevant for inclusion in dermocosmetic formulations, scalp care products, and anti-itch topical preparations.
Anti-inflammatory & Antioxidant Activity
Osthole has demonstrated the ability to modulate inflammatory mediators in preclinical research, positioning it as a potential functional ingredient in anti-aging, immune support, and inflammation-management supplement lines.
Note: The above functional information is based on existing research literature and does not constitute medical claims. Formulators are advised to comply with applicable regulatory frameworks in their respective markets.
Industry Applications
Cnidium Monnieri Extract Osthole finds application across a broad range of industries and product categories:
- Dietary Supplements & Nutraceuticals: Capsules, tablets, softgels, and powder blends for men's health, bone health, and vitality formulas
- Functional Foods & Beverages: Standardized herbal extracts for incorporation into functional product lines
- Cosmetics & Personal Care: Topical creams, serums, scalp treatments, and anti-itch formulations
- Traditional Herbal Medicine (TCM/Ayurveda-inspired): Compound herbal formulations for licensed practitioners
- Pharmaceutical Intermediates: High-purity Osthole 98% for research, analytical reference, and semi-synthesis applications
- Animal Nutrition: Emerging use in animal health and veterinary supplement formulations
Quality Standards & Certifications
Extract Makers operates a fully integrated GMP-certified manufacturing facility that adheres to internationally recognized quality management systems. Our Cnidium Monnieri Extract Osthole is produced and tested under the following standards and certifications:
- ✅ GMP (Good Manufacturing Practice) — Pharmaceutical-grade production environment
- ✅ ISO 9001 — Quality management system certification
- ✅ ISO 22000 — Food safety management certification
- ✅ HACCP — Hazard analysis and critical control points compliance
- ✅ Kosher Certified — Suitable for Kosher-compliant product development
- ✅ Halal Certified — Suitable for Halal-compliant formulations
- ✅ FDA Facility Registration — Registered with the U.S. Food and Drug Administration
Each production batch is accompanied by a full Certificate of Analysis (COA), including HPLC assay results, heavy metal testing, microbiological testing, moisture content, and residual solvent analysis. Documentation packages including MSDS, allergen statements, and country-of-origin declarations are available upon request.
Free Sample Availability
Extract Makers understands that ingredient quality must be verified before purchase commitments are made. We offer complimentary samples — typically 10g to 20g — of Cnidium Monnieri Extract Osthole for qualified buyers to evaluate appearance, solubility, and analytical performance against their specifications.
For high-purity grades such as Osthole 98%, sample availability and associated costs may be subject to confirmation. Please reach out to our team directly to arrange sample dispatch and discuss your specific evaluation requirements.
Packaging Options
Extract Makers provides flexible packaging configurations designed to support both trial orders and large-scale commercial procurement:
| Order Scale | Packaging Format |
|---|---|
| Small / Trial Orders | 1 kg – 5 kg aluminum foil bags |
| Mid-size Orders | 10 kg – 20 kg export cartons |
| Bulk / Commercial Orders | 10 kg – 30 kg fiber drums |
Private Label & Custom Packaging
For brand owners, distributors, and retailers seeking ready-to-sell packaging, Extract Makers offers full private label services. We can customize packaging with your brand logo, product name, and design specifications — significantly reducing your in-house packaging workload and time-to-market. This service is particularly valuable for companies launching new supplement lines or expanding into new regional markets.
Shipping & Logistics
Extract Makers ships globally and offers a range of freight solutions tailored to order volume:
- Express Courier (Orders Below 1 Ton): DHL, FedEx, UPS, EMS, and other major courier networks
- Railway Freight: Cost-effective overland shipping option for bulk orders to applicable destinations
- Sea Freight: Full container load (FCL) and less-than-container load (LCL) options for large-volume international shipments
All shipments are accompanied by complete export documentation, including commercial invoices, packing lists, certificates of origin, and phytosanitary or health certificates where required.
After-Sales Support & Quality Guarantee
Extract Makers is committed to long-term supplier partnerships rather than one-time transactions. Our post-purchase service commitments include:
- Shelf Life Guarantee: Most products carry a 2-year shelf life from date of manufacture, with quality assured for the full duration under recommended storage conditions
- Hassle-Free Return Policy: If any product fails to meet the agreed specification, we offer refunds proportional to the quantity returned
- Responsive Technical Support: Our team of product specialists is available to assist with formulation questions, regulatory documentation requests, and reorder management
Storage Recommendations
To maintain the stability and potency of Cnidium Monnieri Extract Osthole throughout its shelf life:
- Store in a cool, dry, and well-ventilated environment
- Recommended storage temperature: Below 25°C
- Protect from direct sunlight, heat, and humidity
- Keep containers tightly sealed after opening to prevent moisture absorption and oxidation
- Shelf life: 24 months from the date of manufacture under proper storage conditions
Why Source Cnidium Monnieri Extract Osthole from Extract Makers?
For ingredient buyers, private label brands, and global distributors evaluating supply partners, Extract Makers offers a compelling set of advantages:
- Full vertical integration — From raw material sourcing through to finished extract and custom packaging
- Multi-grade availability — A complete range from 10:1 ratio extracts to 98% pure Osthole in a single supply chain
- Robust quality documentation — COA, MSDS, Halal/Kosher/GMP certificates, and more available per batch
- Flexible MOQ and packaging — Designed to support startups, growing brands, and established enterprises alike
- Reliable international logistics — Established export experience to North America, Europe, Southeast Asia, and beyond
- Dedicated account management — Personalized service for sample requests, formulation guidance, and order coordination
Request a Sample or Obtain a Quote
To request a complimentary sample of Cnidium Monnieri Extract Osthole, discuss pricing for your target volume, or inquire about custom extraction grades and private label services, please contact our team directly:
📧 Email: [email protected]
Our specialists are ready to provide product documentation, technical data sheets, and logistics support to help you evaluate and integrate this ingredient into your product pipeline.
Extract Makers carries a portfolio of more than 2,000 botanical extracts, standardized plant actives, and nutritional ingredients. If you are sourcing a specific plant extract or active compound that is not listed on our website, please contact us directly — our full catalog extends well beyond what is published online.
